The Shala Daily

YOGA β€’ PHILOSOPHY β€’ LIFE

May 9, 2026
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Mindfulness Matched Lexapro for Anxiety in Clinical Trial

A randomized controlled trial found mindfulness-based stress reduction was as effective as the prescription drug escitalopram (Lexapro) for treating anxiety disorders.

πŸ•‰οΈ KEY CONCEPTS

svadhyaya
self-study, self-observation
vairagya
non-attachment, dispassion
pratyahara
sense withdrawal
upeksha
equanimity

A 2022 randomized controlled trial compared mindfulness-based stress reduction (MBSR) to escitalopram, commonly known as Lexapro, in treating anxiety disorders. The study enrolled 276 participants and ran for 8 weeks. The result: MBSR was statistically non-inferior to the medication.

This does not mean meditation replaces medication for everyone. But it does mean that in a rigorous clinical setting, the two approaches produced comparable outcomes. Participants in the MBSR group followed a structured program of meditation, body scanning, and gentle movement.

For practitioners, the takeaway is that mindfulness is not a soft alternative. It performed on par with a widely prescribed pharmaceutical in a controlled trial. The study adds weight to the idea that consistent contemplative practice can produce clinically meaningful changes in anxiety.

Source: Yoga Research: Mental Health & Trauma on ashtanga.tech. Original research.

"MBSR was non-inferior to escitalopram for the treatment of anxiety disorders."

β€” JAMA Psychiatry

Mindfulness practice was statistically equivalent to a leading anxiety medication.

β€” MJH
Original Article: "Yoga Research: Mental Health & Trauma", ashtanga.tech

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